GRK5: big-hearted target?
نویسندگان
چکیده
منابع مشابه
Accelerating Alzheimer’s pathogenesis by GRK5
G protein-coupled receptors (GPCRs) mediate a wide variety of physiological function. GPCR signaling is negatively regulated by the receptor desensitization, a procedure initiated by a group of kinases, including GPCR kinases (GRKs). Studies using gene-targeted mice revealed that deficiency of a particular GRK member led to dysfunction of a highly selective group of GPCRs. In particular, for ex...
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ژورنال
عنوان ژورنال: Science-Business eXchange
سال: 2008
ISSN: 1945-3477
DOI: 10.1038/scibx.2008.694